Found 24 matching trials
NKG2D/CLDN18.21 CAR-T(KD-496) in the Treatment of Advanced NKG2DL+/CLDN18.2+ Solid Tumor PHASE1 This is a Phase 1, single-arm, single-center, open-label study to evaluate ...
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Beijing Cancer Hospital
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A Phase III Randomized Study in CLDN18.2-positive Unresectable Locally Advanced Gastric Cancer Patients PHASE3 An open-label, randomized, comparative phase II study including patients wi...
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Chinese PLA General Hospital, Beijing
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Mesothelin and Claudin 18.2 Dual-Target CAR-T Therapy in Advanced Pancreatic Cancer PHASE1 Autologous T-cells engineered to express CARs targeting Mesothelin and Clau...
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District One Hospital
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Clinical Study of LY011 in the Treatment of Advanced Pancreatic Cancer EARLY_PHASE1 CLDN 18.2 chimeric antigen receptor T cells Clinical research plan for the ...
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The Affiliated Hospital of Xuzhou Medical University
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Treatment of Advanced Malignant Solid Tumors With Claudin18.2CAR-T NA The efficacy of advanced pancreatic cancer and gastric cancer needs to be f...
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Study to Evaluate the Safety, Tolerance, Pharmacokinetics and Preliminary Efficacy of IBI345 PHASE1 A phase Ia study to evaluate the safety, tolerance, pharmacokinetics and pr...
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The First Affiliated Hospital of Soochow University
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Biomarker-Guided Dual-Target CAR-T Cells for Advanced Solid Tumors PHASE1 This is a multicenter, open-label, Phase 1/2 master protocol evaluating aut...
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Peking University Shenzhen Hospital
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Claudin 18.2-Targeted Chimeric Antigen Receptor T-cells in Subjects With Unresectable, Locally Advanced, or Metastatic Gastric, Gastroesophageal Junction (GEJ), Esophageal, or Pancreatic Adenocarcinoma PHASE1 This is a Phase 1, Open-Label, Dose Escalation and Expansion, Multicenter S...
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Active Not Recruiting
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Moffitt Cancer Center
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Exploratory Clinical Trial on the Safety, Efficacy, and Pharmacokinetics of XKDCT086 (iPD-1-Claudin18.2-CAR-T) in Claudin 18.2 Positive Advanced Solid Malignant Tumors: a Single Center, Single Arm, Dose-increasing Trial NA The goal of this clinical trial is to assessing the safety and tolerability...
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The Affiliated Hospital of Qingdao University
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A Study to Evaluate the Efficacy and Safety of CT041 After Adjuvant Chemotherapy for Pancreatic Cancer PHASE1 An open-label, single-arm, multicenter, Phase Ib clinical trial to evaluate...
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Beijing Cancer Hospital
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